Author

Natalia Kakko von Koch

Aalto UniversityORCID 0000-0002-8807-595XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Approach:experimental assay· 1 Assay:long-read sequencing· 1 Approach:statistical model· 1 Organism:yeast· 1

Frequent Co-Authors

Paula JouhteniD· 2 shared An Nguyen· 1 shared Andreas Møllerhøj VestergaardiD· 1 shared Ao Ying· 1 shared Biswajyoti SahuiD· 1 shared Chunhao GuiD· 1 shared Divyesh PateliD· 1 shared Esa PitkäneniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersSynthetic Biology

Paula JouhtenORCID

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2 papers

Recent·Most cited

Synthetic BiologyMetabolic EngineeringPeer-reviewedApr 2, 2026

Adaptive evolution of engineered Saccharomyces cerevisiae in favored and unusual chemical environments

Natalia Kakko von Koch, An Nguyen, Olli Lohilahti…·Paula Jouhten

This study investigates how Darwinian selection affects engineered traits in yeast by evolving strains with pigment production pathways under different carbon sources.

2 citations

yeastexperimental assay

𝕏 PostBluesky

BioinformaticsbioRxivPreprintOct 31, 2025

Compound-specific DNA adduct profiling with nanopore sequencing and IonStats

Yrjö Koski, Divyesh Patel, Natalia Kakko von Koch…·Esa Pitkänen

This study develops IonStats, a toolkit for profiling DNA adducts using nanopore sequencing, revealing compound-specific effects on sequencing data.

DOI 10.1101/2025.10.31.685820

long-read sequencingstatistical model

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