Divyesh Patel

The paper shows classical enhancers influence 3D genome structure by linking DNA sequence to transcriptional condensates and chromatin organization through specific transcription factors.

This study develops IonStats, a toolkit for profiling DNA adducts using nanopore sequencing, revealing compound-specific effects on sequencing data.

The paper investigates how inhibiting chromatin modifier enzymes in cancer cells leads to cell-type-specific derepression of transposable elements, enhancing immune response through distinct mechanisms.

The paper introduces a new antibody capture method to accurately capture G4 structures in human cells and shows that G4 formation is constrained by sequence properties and nuclear environment.

The paper identifies tissue-specific transposable element enhancers in colorectal and liver cancers using unbiased reporter assays and shows their association with distinct transcription factors and differentially expressed genes.

The paper investigates chromosomal chimeras in human cell cultures, showing their occurrence at genomic repeats and regulation by stress and CGGBP1 depletion.

The paper shows CGGBP1-dependent CTCF-binding sites inhibit ectopic transcription from the SV40 promoter by acting as transcription barriers.

The paper shows that CGGBP1 regulates cytosine methylation at CTCF-binding sites deterministically, influencing CTCF occupancy and function.

This study shows CGGBP1 regulates CTCF occupancy at repeats and their chromatin barrier function through ChIP-sequencing and histone modification analysis.