Thomas S. van Zanten

The paper shows that two classes of myosins organize distinct membrane domains through active forces, enabling spatial segregation of nanoclusters and modulating information transduction.

MagPiezo pairs 19 nm anti-Piezo1-conjugated ZnMnFe2O4 nanoparticles with a 1 Hz, <40 mT magnetic applicator to generate piconewton torque that gates endogenous Piezo1 channels in human endothelial cells.

The paper introduces a solvatochromic probe, C3L, to measure membrane order at the plasma membrane leaflet level, revealing asymmetry and local modulation by transbilayer interactions.

The paper investigates stereocilia formation in mouse cochlear hair cells using microscopy and actin analysis, revealing early actin dynamics and structural changes during development.

This study identifies integrin receptor signaling as a driver of GPI-anchored protein nanoclusters through acto-myosin activity and vinculin coupling.