Marten P. Smidt

The paper identifies distinct progenitor populations in human ganglionic eminences, their gene regulatory networks, and lineage trajectories using single-nucleus transcriptomics and spatial transcriptomics.

The paper investigates the role of H3K79 methylation and Dot1l in neuronal aging and Parkinson's disease by analyzing their effects on gene expression in dopaminergic neurons.

The paper confirms that Pitx3ak mice do not entrain behavioral and metabolic rhythms to light-dark cycles but can entrain to feeding schedules, suggesting a minimal dopamine neuron population is sufficient for food entrainment.

This study shows Tcf4 is critical for cortical differentiation during development, with loss leading to brain malformations similar to Pitt-Hopkins Syndrome.

This study shows that EZH2 is essential for specifying the isthmic region by influencing the Isthmic organizer and repressing Otx2 in the hindbrain.

This study investigates the role of Lmx1b in the post-mitotic survival of mesodiencephalic dopaminergic neurons, revealing its impact on specific subgroups in different brain regions.

This study shows that EZH2 is critical for mdDA neuron development and maintains their subset identity and survival in adulthood.