Arturo Álvarez-Buylla

The paper identifies a novel ependymal cell type (E2) in the forebrain that senses cerebrospinal fluid signals via specialized cilia and Smoothened receptor.

The paper provides a high-resolution molecular and cellular analysis of Broca's area and motor cortex across developmental stages, identifying distinct cellular signatures and vulnerabilities to neurodevelopmental disorders.

This study maps the spatial and molecular changes in neural progenitor cells in the human dentate gyrus from gestation to postnatal stages, showing a decline in neurogenic potential and transition to astrocytic features.

The paper identifies distinct progenitor populations in human ganglionic eminences, their gene regulatory networks, and lineage trajectories using single-nucleus transcriptomics and spatial transcriptomics.

This study uses single-cell analysis of dup15q syndrome to identify developmental and postnatal molecular changes in autism, revealing cell-type specific dysregulation and shared vulnerabilities with idiopathic ASD.

This study shows that the identity of MGE-derived cortical interneurons can be dynamically influenced by their environment, with human 3D models promoting Pvalb expression over Sst.

This study identifies B2 cells as the primary neural stem cells in the adult mouse V-SVZ, replacing B1 cells postnatally to sustain neurogenesis.

This study maps the molecular and cellular dynamics of the developing human neocortex using single-nucleus data, revealing gene regulatory networks and a cancer-related progenitor subtype.

This study shows that transplanting MGE-derived interneurons into adult mouse visual cortex induces ocular dominance plasticity, with activity and response tuning influenced by host locomotor state.

The paper shows that deletion of the Pcdhγc4 isoform increases cortical interneuron cell death, while viral expression rescues it, highlighting its critical role in regulating survival during programmed cell death.

The paper shows that intrinsic developmental origins and local signals shape septal astrocyte identity through distinct molecular and morphological features in medial and lateral septal nuclei.

This study creates a cross-species proteomic map of synapse development in human, macaque, and mouse neocortex, revealing slower human PSD maturation and its potential link to neoteny.

This study identifies Prdm16 and Vcam1 as regulators of postnatal radial glia disappearance and the termination of cortical neurogenesis.

This study shows that interneurons continue to migrate into the human entorhinal cortex postnatally, with distinct lineage contributions and maturation patterns identified using single-nuclei RNAseq.

The paper uses single-cell and single nucleus sequencing to identify two distinct adult neurogenic lineages in the mouse V-SVZ, marked by specific gene expression patterns.

The paper identifies molecular subtypes of human interneuron progenitors and immature interneurons using single-cell RNA sequencing and compares them to mouse data, revealing species-specific gene programs.

This study identifies Pcdh-γ cluster genes as critical regulators of programmed cell death in cortical interneurons through cell-autonomous and non-cell autonomous mechanisms.

The paper shows that transplanted inhibitory neurons induce but do not maintain ocular dominance plasticity in the host visual cortex.