Author

Mangyu Choe

The University of Texas Southwestern Medical CenterORCID 0000-0002-8889-7494Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cancer Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

Ariella B. HankeriD· 1 shared Caroline HaueriD· 1 shared Denis V. TitoviD· 1 shared Hijai R. Shin· 1 shared Isaac S. Chan· 1 shared Javier García‐BermúdeziD· 1 shared Ling CaiiD· 1 shared Lingjie SangiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCancer Biology

Ariella B. HankerORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Tumor control of lysosomal acidification promotes lipoprotein assimilationand ferroptosis resistance

Renfei Wu, Sheng‐Chieh Hsu, Lingjie Sang, Miaomiao Yu, Yoon Jung Kim, Mangyu Choe, Caroline Hauer, Ling Cai, Ariella B. Hanker, Isaac S. Chan, Hijai R. Shin, Javier García‐Bermúdez

This study identifies ZNF217 as a driver of tumor lysosomal function and ferroptosis resistance by maintaining lysosomal acidification and lipoprotein assimilation.

bioRxiv · Aug 26, 2026 · PreprintCancer Biology

Data-driven model of glycolysis shows that allostery maintains high ATP levels while mass action controls flux and energy of ATP hydrolysis

Mangyu Choe, Tal Einav, Rob Phillips, Denis V. Titov

Biophysical Journal · Apr 3, 2025Peer-reviewedSystems Biology