Javier García‐Bermúdez

This study identifies ZNF217 as a driver of tumor lysosomal function and ferroptosis resistance by maintaining lysosomal acidification and lipoprotein assimilation.

The paper develops a biosensor to monitor α-ketoglutarate in human cells and identifies a mitochondrial-to-nuclear pathway regulating chromatin methylation.

This study shows that fatty acid metabolism regulates plasma membrane cholesterol accessibility through ATGL-dependent phospholipid remodeling, affecting membrane fluidity and cholesterol signaling.

This study identifies glycosaminoglycan-mediated lipoprotein uptake as a mechanism by which cancer cells resist ferroptosis and lipid oxidative stress.