Yoon Jung Kim

This study identifies ZNF217 as a driver of tumor lysosomal function and ferroptosis resistance by maintaining lysosomal acidification and lipoprotein assimilation.

The paper develops a biosensor to monitor α-ketoglutarate in human cells and identifies a mitochondrial-to-nuclear pathway regulating chromatin methylation.

This study shows that aging-related retrotransposon activation in stromal cells promotes Dnmt3a-mutant clonal hematopoiesis through inflammation.

This study identifies cis and trans regulatory mechanisms governing ecDNA segregation, showing H3K27ac and bromodomain proteins mediate interactions, while inactive Pol II facilitates attachment.

This study shows ecDNA-driven oncogene super-expressors create an immunoevasive tumor microenvironment in PDAC by promoting myCAF expansion and suppressing T cell infiltration.

This study shows mutant IDH reprograms neural progenitor cell fate by silencing Gsx2, promoting gliomagenesis through lineage switching.

This study identifies PARP7 as a key regulator of C/EBPβ-dependent adipogenesis and shows it senses nuclear NAD+ levels to control gene expression and lipid production in mammary glands.