Author

Samar A. Tolba

University of Wisconsin–MadisonORCID 0000-0002-8902-8311Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Ashley M. SidebottomiD· 1 shared Daniel Amador‐NogueziD· 1 shared Evan A. ChrisleriD· 1 shared Federico E. ReyiD· 1 shared Guillermo Martinez BoggioiD· 1 shared Jake B. HermansoniD· 1 shared Lauren N. LucasiD· 1 shared Manpreet KauriD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperPhysiology

Ashley M. SidebottomORCID

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1 paper

Recent·Most cited

Gut microbes mediate the synergistic effects of dietary cholesterol and saturated fat in driving fibrosing MASH

Jake B. Hermanson, Samar A. Tolba, Md. Amran Gazi, Evan A. Chrisler, Manpreet Kaur, Ashley M. Sidebottom, Yong-Jun Liu, Guillermo Martinez Boggio, Lauren N. Lucas, Daniel Amador‐Noguez, Federico E. Rey, Vanessa Leone

This study shows that dietary cholesterol and saturated fat together drive fibrosing MASH via gut microbiota changes, specifically increasing Parasutterella spp. and activating hepatic stellate cells.

Gut Microbes · May 10, 2026Peer-reviewedPhysiology