PhysiologyGut MicrobesPeer-reviewed
Gut microbes mediate the synergistic effects of dietary cholesterol and saturated fat in driving fibrosing MASH
Jake B. Hermanson, Samar A. Tolba, Md. Amran Gazi…·Vanessa Leone
This study shows that dietary cholesterol and saturated fat together drive fibrosing MASH via gut microbiota changes, specifically increasing Parasutterella spp. and activating hepatic stellate cells.
2 citations