Author

Robert J. Kimmerling

Koch Institute for Integrative Cancer Research At MITORCID 0000-0002-8920-336XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Mark M. StevensiD· 2 shared Scott R. ManalisiD· 2 shared Ye ZhangiD· 2 shared Alan DenAdeliD· 1 shared Aleigha Lawless· 1 shared Alejandro J. Gupta· 1 shared Alex K. ShalekiD· 1 shared Alexandria Van ScoykiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersBiophysics

Mark M. StevensORCID

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2 papers

Recent·Most cited

Buoyant mass reveals distinct T cell states predictive of checkpoint response

Jiaquan Yu, Ye Zhang, Sarah M. Duquette, Robert J. Kimmerling, James C. Kostas, Krystal K. Lum, Rachel LaBella, Selim Olçum, Madeleine Vacha, Steve Wasserman, Reginald Aikins, Katie Katsis, Thomas R. Usherwood, Sonia Cohen, Teresa Dinter, , Scott R. Manalis

The paper uses buoyant mass to identify distinct T cell states that predict response to immune checkpoint therapy in melanoma patients.

bioRxiv · Sep 26, 2024 · PreprintBiophysics

Mutation and cell state compatibility is required and targetable in Ph+ acute lymphoblastic leukemia minimal residual disease

Peter S. Winter, Michelle L. Ramseier, Andrew W. Navia, Sachit D. Saksena, Haley Strouf, Nezha Senhaji, Alan DenAdel, Mahnoor Mirza, Hyun Hwan An, Laura L. Bilal, Peter S. Dennis, Catharine S. Leahy, Kay Shigemori, Jennyfer Galvez-Reyes, Ye Zhang, , Mark Alan Murakami

This study identifies mutation and transcriptional state compatibility in Ph+ ALL MRD, showing that targeting these interactions can overcome BCR::ABL1 independence and improve MRD monitoring.

bioRxiv · Jun 6, 2024 · PreprintCancer Biology