Cyclin B phosphorylation by PKA safeguards the G2-arrest in vertebrate oocytes
Martina Santoni, Tran Le, Véronique Legros, Guillaume Chevreux, Catherine Jessus, Enrico Maria Daldello
This study identifies Cyclin B2 as a PKA substrate that phosphorylation at S271 represses Cdk1-Cyclin B activation, maintaining G2-arrest in vertebrate oocytes.
bioRxiv · Aug 4, 2026 · PreprintCell Biology