Author

María Ángeles Núñez‐Sánchez

Instituto Murciano de Investigación BiosanitariaORCID 0000-0002-8938-2767Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Bruno Ramos‐MolinaiD· 2 shared María Dolores FrutosiD· 2 shared Adriana MikaiD· 1 shared Alba Oliva‐BolaríniD· 1 shared Ana B. Pérez‐OlivaiD· 1 shared Antonio J. Ruiz‐AlcaraziD· 1 shared Carlos Manuel MartíneziD· 1 shared Dhruvi MakhanasaiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiochemistry

Bruno Ramos‐MolinaORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Hepatic HKDC1 Deletion Alleviates Western Diet-Induced MASH in Mice

Kai Xu, Irene Corona‐Avila, María Dolores Frutos, María Ángeles Núñez‐Sánchez, Dhruvi Makhanasa, Pratham Viral Shah, Grace Guzman, Bruno Ramos‐Molina, Medha Priyadarshini, Md. Wasim Khan

This study shows that deleting HKDC1 in mice reduces Western diet-induced MASH by improving metabolism and reducing inflammation and fibrosis.

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · Feb 27, 2025Peer-reviewedBiochemistry

NLRP1 is activated by palmitic acid and induced in human metabolic dysfunction-associated steatohepatitis

Miriam Pinilla, Eulalia Campos Baños, María Antonia Martínez‐Sánchez, María Sánchez‐Villalobos, Alba Oliva‐Bolarín, Sara Rico‐Chazarra, Antonio J. Ruiz‐Alcaraz, Carlos Manuel Martínez, Adriana Mika, María Dolores Frutos, Bruno Ramos‐Molina, María Ángeles Núñez‐Sánchez, Ana B. Pérez‐Oliva

This study identifies increased NLRP1 expression in MASH liver samples and shows that palmitic acid activates the NLRP1 inflammasome in human cells.

bioRxiv · Nov 11, 2024 · PreprintMolecular Biology