Ana B. Pérez‐Oliva

Gasdermin D mediates a fast transient release of ATP after NLRP3 inflammasome activation before ninjurin 1-induced lytic cell death

This study shows GSDMD-mediated ATP release as an early transient danger signal during NLRP3 inflammasome activation, preceding cell death and IL-1β release.

NLRP1 is activated by palmitic acid and induced in human metabolic dysfunction-associated steatohepatitis

This study identifies increased NLRP1 expression in MASH liver samples and shows that palmitic acid activates the NLRP1 inflammasome in human cells.

UFMylation of MRE11 is essential for telomere length and hematopoietic stem cell survival

The paper identifies UFMylation of MRE11 as critical for telomere length and hematopoietic stem cell survival, showing its role in telomere maintenance without affecting DNA repair.