Cancer BiologyCancer Gene TherapyPeer-reviewed
E2F3 amplification primes bladder cancer cells for premature mitosis.
Kathryn A. Wierenga, Isabel S Nieland, Qingwu Liu…·Bart Westendorp
This study shows E2F3 amplification in bladder cancer cells leads to premature mitosis, which can be targeted by G2/M checkpoint inhibitors.
DOI 10.1038/s41417-026-01084-x