Frank M. Riemers

This study shows E2F3 amplification in bladder cancer cells leads to premature mitosis, which can be targeted by G2/M checkpoint inhibitors.

This study shows that degenerative disc conditions reduce notochordal cell-derived extracellular vesicles release and their ability to promote matrix production in nucleus pulposus cells.

The paper identifies FOXM1 expression levels as a factor in replication stress tolerance in oncogenic RAS-expressing cells using single-cell RNA sequencing and drug combination experiments.