Qingwu Liu

This study shows E2F3 amplification in bladder cancer cells leads to premature mitosis, which can be targeted by G2/M checkpoint inhibitors.

OriGene identifies therapeutic targets by integrating diverse data modalities and outperforms human experts and models in accuracy and robustness.

The paper introduces scMeMo, a mechanistic modeling framework that infers unobserved variables in single cells using diverse measurements, demonstrating its ability to predict protein levels and cell cycle behavior from limited data.