Author

Yannick N. Wadop

The University of Texas at San Antonio Health Science CenterORCID 0000-0002-8955-1874Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 5 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:human· 6 Approach:statistical model· 6 Research Focus:differential expression· 4 Assay:metagenomics· 4 Research Focus:benchmarking· 2 Assay:bulk RNA-seq· 1 Research Focus:database / resource· 1 Approach:diffusion model· 1

Frequent Co-Authors

Bernard FongangiD· 6 shared Sudha S. SeshadriiD· 6 shared Claudia Liliana SatizábaliD· 5 shared Jayandra Jung HimaliiD· 4 shared Alexa BeiseriD· 3 shared Jazmyn A. S. Muhammad· 3 shared Ramachandran Srini VasaniD· 3 shared Rebecca BernaliD· 3 shared

Activity by Year

2022-2025 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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6 shared papersNeuroscience

Bernard FongangORCID

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6 papers

Recent·Most cited

Differential Patterns of Gut and Oral Microbiomes in Hispanic Individuals with Cognitive Impairment

Yannick N. Wadop, Erin Livia Vasquez, Julia J. Mathews, Jazmyn A. S. Muhammad, Rosa V. Pirela, Claudia Liliana Satizábal, Mitzi M. Gonzales, Jeremy A. Tanner, Gladys E. Maestre, Alfred Nji Fonteh, Sudha S. Seshadri, Tiffany F. Kautz, Bernard Fongang

This study examines oral and gut microbiome differences in Hispanic individuals with and without cognitive impairment, finding oral microbiome changes but no synergistic effects with gut microbiomes in ADRD.

Microorganisms · Oct 14, 2025Peer-reviewedNeuroscience

Altered Gut Microbiota Mediates the Association between APOE Genotype and Amyloid-β Accumulation in Middle-Aged Adults

Yannick N. Wadop, Rebecca Bernal, Wepnyu Yembe Njamnshi, Claudia Liliana Satizábal, Alexa Beiser, Agustı́n Ruiz, Alfred Kongnyu NJAMNSHI, Ramachandran Srini Vasan, Sudha S. Seshadri, Jayandra Jung Himali, Bernard Fongang

This study shows that gut microbiota mediates the effect of APOE ε4 genotype on amyloid-β accumulation in middle-aged adults.

Journal of Neurology · Oct 1, 2025Peer-reviewedNeuroscience

Early Metabolic Alterations in Cerebrospinal Fluid Fatty Acid Profiles Linked to Cognitive Decline and All-Cause Dementia

Jacob Apibilla Ayembilla, Yannick N. Wadop, Rebecca Bernal, Biniyam Alemayehu Ayele, Muralidharan Sargurupremraj, Xueqiu Jian, Alfred Kongnyu NJAMNSHI, Sudha S. Seshadri, Alice B. S. Nono Djotsa, Jayandra Jung Himali, Bernard Fongang, Alfred Nji Fonteh

This study identifies CSF fatty acid profiles as better predictors of cognitive decline than traditional biomarkers like Aβ42 and tau, suggesting early metabolic changes in dementia.

bioRxiv · Aug 25, 2025 · PreprintNeuroscience

Adherence to Lifes Essential 8 Enhances Gut Microbiota Diversity and Cognitive Performance

Yannick N. Wadop, Jazmyn A. S. Muhammad, Rebecca Bernal, Claudia Liliana Satizábal, Alexa Beiser, Ramachandran Srini Vasan, Ramnik J. Xavier, Tiffany F. Kautz, Sudha S. Seshadri, Jayandra Jung Himali, Bernard Fongang

This study shows that better adherence to LE8 metrics improves gut microbiota diversity and cognitive performance in the Framingham Heart Study participants.

Frontiers in Microbiomes · Jun 23, 2025Peer-reviewedNeuroscience

Cerebral Small Vessel Disease Burden is Associated with Decreased Abundance of Gut Barnesiella intestinihominis Bacterium in the Framingham Heart Study

Bernard Fongang, Claudia Liliana Satizábal, Tiffany F. Kautz, Yannick N. Wadop, Jazmyn A. S. Muhammad, Erin Livia Vasquez, Julia J. Mathews, Monica Gireud, Amy R. Saklad, Jayandra Jung Himali, Alexa Beiser, José E Cavazos, Michael C. Mahaney, Gladys E. Maestre, Charles S DeCarli, , Sudha S. Seshadri

The paper investigates the relationship between gut microbiota and cerebral small vessel disease markers in the Framingham Heart Study, finding associations between specific bacterial genera and cSVD burden.

Scientific Reports · Aug 21, 2023Peer-reviewedNeuroscience

A meta-analysis of genome-wide association studies identifies new genetic loci associated with all-cause and vascular dementia

Bernard Fongang, Muralidharan Sargurupremraj, Xueqiu Jian, Aniket Mishra, Vincent Damotte, Joshua C. Bis, Fan Kang-Hsien, Gloria Li, Jingyun Yang, Saima Hilal, Maria J. Knol, Maria Pina Concas, Girotto Giorgia, Moeen Riaz, Alexander Guðjónsson, , Sudha S. Seshadri

This study performs a meta-analysis of GWAS to identify new genetic loci associated with all-cause and vascular dementia, revealing shared and distinct risk factors.

bioRxiv · Oct 11, 2022 · PreprintGenetics