Author

Aino Peura

University of HelsinkiORCID 0000-0002-8958-940XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 1 Assay:metabolomics· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Andrei GogaiD· 2 shared Antti O. HiltuneniD· 2 shared Bina PrajapatiiD· 2 shared Daniel NicoriciiD· 2 shared Johanna M. AnttilaiD· 2 shared Johanna MattsoniD· 2 shared Juha T. KlefströmiD· 2 shared July AungiD· 2 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Andrei GogaORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Microtubule Inhibition Triggers MYC-Mediated Immunogenic Cell Death in Breast Cancer

Ruixian Liu, July Aung, Aino Peura, Antti O. Hiltunen, Linda Id, Mariel Savelius, Martina Peltonen, Rita Turpin, Natasha Salmelin, Johanna M. Anttila, Topi Aulis Tervonen, Ilida Suleymanova, Daniel Nicorici, Minna Mutka, Johanna Mattson, , Juha T. Klefström

The paper identifies microtubule inhibitors as inducers of immunogenic cell death in MYChigh TNBC, linking MYC-dependent DAMP release to immune activation and tumor protection.

bioRxiv · Aug 26, 2025 · PreprintCancer Biology

Complex I Drives Glutamine-Dependent TCA Cycle to Support Viability of MYChigh Breast Cancer Cells

Johanna M. Anttila, Mariel Savelius, Juhi Somani, Daniel Nicorici, Pauliina Munne, Linda Id, Aino Peura, Antti O. Hiltunen, July Aung, Ryan Awadhpersad, Bina Prajapati, Martina Peltonen, Hanna Ala-Hongisto, Prson Gautam, Mika J. Välimäki, , Juha T. Klefström

This study identifies enhanced mitochondrial respiration and glutamine-dependent TCA cycle as vulnerabilities in MYChigh breast cancer cells, showing synthetic lethality with complex I inhibitors.

bioRxiv · May 27, 2025 · PreprintCancer Biology