Ruixian Liu

Biomimetic porous silicon for rationally engineered combination therapy to induce immunogenic cell death

This study identifies JQ1 and 45°C as optimal components for a combined chemo-photothermal therapy to induce immunogenic cell death in metastatic breast cancer.

Microtubule Inhibition Triggers MYC-Mediated Immunogenic Cell Death in Breast Cancer

The paper identifies microtubule inhibitors as inducers of immunogenic cell death in MYChigh TNBC, linking MYC-dependent DAMP release to immune activation and tumor protection.

Patient-derived tumor explant models of tumor immune microenvironment reveal distinct and reproducible immunotherapy responses

The paper evaluates immunomodulatory drug responses in patient-derived tumor explant models of breast and renal cancer, finding reproducible gene expression and cytokine changes across models.