Jieun Oh

This study examines how sex and ancestry influence the genomic heterogeneity of pancreatic adenocarcinoma across multiple datasets.

The paper quantifies sex differences in the cancer proteome across eight cancer types, identifying sex-differential protein abundance and linking some differences to copy number aberrations.

ROCIT classifies tumor or non-tumor origin of reads from bulk long-read sequencing with high accuracy, improving somatic variant calling in tumors.

Metapipeline-DNA automates comprehensive analysis of DNA sequencing data from raw reads to visualization, supporting germline and somatic genomic features.

The paper investigates how patient sex affects cancer cell function by analyzing gene essentiality and drug sensitivity across 1,209 cell lines.

The paper quantifies the impact of genome build differences on variant calling and introduces StableLift, an algorithm to predict cross-build variant stability.

The paper identifies a non-canonical role of DNA mismatch repair (MMR) in repairing methylation damage in non-dividing cells, contributing to mutational signatures in cancer.