Amanda Day

This study establishes patient-derived KS xenografts that maintain KSHV infection and recapitulate KS tumor gene signatures, enabling analysis of tumor microenvironment cell communications.

This study shows that HDAC inhibition with entinostat enhances immunotherapy response in SCLC by reprogramming tumor immunology and neuroendocrine status.

This study directly detects meiotic DSBs and resection in vertebrates using END-seq on mouse spermatocytes, identifying a novel recombination intermediate regulated by ATM and PRDM9.