Temporal Single Cell Analysis of Leukemia Microenvironment Identifies Taurine-Taurine Transporter Axis as a Key Regulator of Myeloid Leukemia
Sonali Sharma, Benjamin J. Rodems, Cameron D. Baker, Christina M. Kaszuba, Edgardo I. Franco, Bradley R. Smith, Takashi Ito, Kyle Swovick, Kevin A. Welle, Yi Zhang, Philip J. Rock, Francisco A. Chaves, Sina Ghaemmaghami, Laura Maria Calvi, Archan Ganguly, , Jeevisha Bajaj
This study identifies the taurine-taurine transporter axis as a critical regulator of myeloid leukemia using temporal single-cell RNA-sequencing and functional experiments.
Nature · May 14, 2025Peer-reviewedCancer Biology