Author

J Ignacio Gutierrez

Weill Cornell MedicineORCID 0000-0002-9017-8384Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:yeast· 3 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Assay:imaging· 1 Approach:simulation· 1 Approach:statistical model· 1

Frequent Co-Authors

Gregory P. BrittinghamiD· 2 shared Liam J. HoltiD· 2 shared Alex S. HolehouseiD· 1 shared Arnob DuttaiD· 1 shared Claudia Edgar· 1 shared Craig L. PetersoniD· 1 shared David FenyöiD· 1 shared Jessica K. TyleriD· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersMolecular Biology

Gregory P. BrittinghamORCID

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Author profile →

3 papers

Recent·Most cited

Overexpression of Ssd1 and calorie restriction extend yeast replicative lifespan by preventing deleterious age-dependent iron uptake

J Ignacio Gutierrez, Claudia Edgar, Jessica K. Tyler

bioRxiv · Sep 2, 2025Cell Biology

SWI/SNF senses carbon starvation with a pH-sensitive low complexity sequence

J Ignacio Gutierrez, Gregory P. Brittingham, Yonca Karadeniz, Kathleen D. Tran, Arnob Dutta, Alex S. Holehouse, Craig L. Peterson, Liam J. Holt

The paper shows that the SWI/SNF complex uses a pH-sensitive low complexity sequence to sense carbon starvation in yeast.

eLife · Feb 7, 2022Peer-reviewedMolecular Biology

The largest SWI/SNF polyglutamine domain is a pH sensor

J Ignacio Gutierrez, Gregory P. Brittingham, Xuya Wang, David Fenyö, Liam J. Holt

The paper shows that a polyglutamine domain in the yeast SWI/SNF complex functions as a pH sensor for transcriptional regulation during carbon starvation.

bioRxiv · Apr 17, 2018 · PreprintGenetics