Author

Xuya Wang

Bristol-Myers Squibb (United States)ORCID 0000-0001-5538-5217Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:yeast· 1

Frequent Co-Authors

David FenyöiD· 3 shared Liam J. HoltiD· 2 shared D.R. ManiiD· 1 shared David J. KahleriD· 1 shared David M. TruongiD· 1 shared Emily M. AdneyiD· 1 shared Gregory P. BrittinghamiD· 1 shared J Ignacio GutierreziD· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersGenetics

David FenyöORCID

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3 papers

Recent·Most cited

BioinformaticsbioRxivPreprintJul 15, 2021

Modeling transcriptional profiles of gene perturbation with deep neural network

Wenke Liu, Xuya Wang, D.R. Mani, David Fenyö

The paper uses deep neural networks to predict gene perturbation from transcriptional profiles, achieving 74.9% accuracy but with limited generalizability due to data consistency issues.

DOI 10.1101/2021.07.15.452534

bulk RNA-seqdeep learning

𝕏 PostBluesky

GeneticsGeneticsPeer-reviewedOct 30, 2019

Comprehensive scanning mutagenesis of human retrotransposon LINE-1 identifies motifs essential for function

Emily M. Adney, Matthias Thomas Ochmann, Srinjoy Sil…·Jef D. Boeke

The paper identifies functionally important regions in ORF1p and ORF2p of human LINE-1 through trialanine mutagenesis, showing most mutants lose retrotransposition activity.

24 citations

humanexperimental assay

𝕏 PostBluesky

GeneticsbioRxivPreprintApr 17, 2018

The largest SWI/SNF polyglutamine domain is a pH sensor

J Ignacio Gutierrez, Gregory P. Brittingham, Xuya Wang…·Liam J. Holt

The paper shows that a polyglutamine domain in the yeast SWI/SNF complex functions as a pH sensor for transcriptional regulation during carbon starvation.

7 citations

yeastexperimental assay

𝕏 PostBluesky