Liat Amir-Zilberstein

Single-cell transcriptomics reveals the impact of sex and age in the healthy human liver

This study uses single-cell RNA sequencing to analyze how sex and age affect gene expression and cellular interactions in healthy human liver cells.

Spatial transcriptomics of healthy and fibrotic human liver at single-cell resolution

The paper uses spatial transcriptomics to map cell types and their spatial organization in healthy and fibrotic human liver, identifying changes in hepatocyte populations during fibrosis.

Systematically characterizing the roles of E3-ligase family members in inflammatory responses with massively parallel Perturb-seq

The paper uses Perturb-seq to systematically study 1,130 E3 ligases and their roles in inflammatory responses in dendritic cells, revealing co-functional modules and genetic interactions.

Cell-subtype specific effects of genetic variation in the aging and Alzheimer cortex

The paper identifies cell-type and cell-subtype specific eQTLs in aging human cortex, revealing variant effects on gene expression and disease associations.

A single-cell and spatial atlas of autopsy tissues reveals pathology and cellular targets of SARS-CoV-2

This study creates a single-cell and spatial atlas of autopsy tissues from COVID-19 patients, revealing altered cellular responses and potential therapeutic targets.

Shear forces drive precise patterning of hair cells in the mammalian inner ear

This study shows that shear forces and local repulsion drive the formation of the checkerboard pattern of hair cells in the mammalian inner ear.