Ting Du

This study shows mechanical ventilation and anesthesia impair glymphatic function in mice, leading to delirium-like behavior.

This paper develops an AI velocimetry method to infer 3D CSF flow in mice, including pressure, shear stress, and flow rates, with uncertainty quantification.

This study examines how AQP4 deletion affects glymphatic function using diffusion MRI techniques, finding altered brain fluid dynamics and reduced glymphatic influx in AQP4 KO mice.

The paper demonstrates that bulk CSF flow in periarterial spaces is not an artifact of injection, using a dual-syringe system that prevents volume changes and pressure increases.

This study confirms that AQP4 is essential for glymphatic fluid and solute transport in the rodent brain, as Aqp4 disruption reduces CSF influx and amyloid-beta efflux.