Whole brain delivery of an instability-prone Mecp2 transgene improves behavioral and molecular pathological defects in mouse models of Rett syndrome
Mirko Luoni, Serena Gea Giannelli, Marzia Tina Indrigo, Antonio Niro, Luca Massimino, Angelo Iannielli, Laura Passeri, Fabio Russo, Giuseppe Morabito, Piera Calamita, Silvia Gregori, Benjamin E. Deverman, Vania Broccoli
AAV-PHP.eB-mediated delivery of an instability-prone Mecp2 transgene improves behavioral and molecular defects in Mecp2 mutant mice without severe toxicity.
eLife · Mar 24, 2020Peer-reviewedNeuroscience