Author

Louis‐Jan Pilaz

University of South DakotaORCID 0000-0002-9035-1327Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Approach:experimental assay· 3 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:protein design· 1

Frequent Co-Authors

Brandon L. MeyerinkiD· 3 shared A K KleiniD· 1 shared Ariana C. Edwards· 1 shared Claire E. ShamberiD· 1 shared Claire M. Evans· 1 shared Claire M. KittockiD· 1 shared Debra L. SilveriD· 1 shared Elizabeth R. Aaseng· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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3 shared papersNeuroscience

Brandon L. MeyerinkORCID

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4 papers

Recent·Most cited

NeuroscienceFrontiers in NeurosciencePeer-reviewedFeb 28, 2025

Mutation in Wdr45 leads to early motor dysfunction and widespread aberrant axon terminals in a beta-propeller protein associated neurodegeneration (BPAN) patient-inspired mouse model

Brandon L. Meyerink, Krishna S. Karia, Mitchell J. Rechtzigel…·Louis‐Jan Pilaz

This study creates a BPAN patient-inspired mouse model with a Wdr45 mutation, revealing motor dysfunction, axon terminal abnormalities, and disrupted pathways in the brain.

1 citation

mousespatial transcriptomics

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NeurosciencebioRxivPreprintJun 18, 2024

AAV-mediated gene transfer of WDR45 corrects neurologic deficits in the mouse model of beta-propeller protein-associated neurodegeneration

Maria Carla Carisi, Claire E. Shamber, Martha Bishop…·Yulia Grishchuk

This study shows that AAV-mediated WDR45 gene transfer rescues neurologic deficits and autophagy defects in a mouse model of BPAN.

DOI 10.1101/2024.06.18.599588

mouseexperimental assay

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Developmental BiologyDevelopmentPeer-reviewedAug 22, 2022

Breasi-CRISPR: an efficient genome editing method to interrogate protein localization and protein-protein interactions in the embryonic mouse cortex

Brandon L. Meyerink, Pratiksha KC, Neeraj K. Tiwari…·Louis‐Jan Pilaz

Breasi-CRISPR efficiently tags endogenous proteins in embryonic mouse brains for localization and interaction studies, enabling visualization and interactome analysis.

14 citations

mouseprotein structure

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NeurosciencebioRxivPreprintJul 30, 2020

Subcellular mRNA localization and local translation of Arhgap11a in radial glial cells regulates cortical development

Louis‐Jan Pilaz, Kaumudi Joshi, Jing Liu…·Debra L. Silver

The paper shows that Arhgap11a mRNA localization and local translation in radial glial cells control cortical development by regulating RGC morphology and neuron positioning.

12 citations

mousehuman

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