Valentı́n Fuster

Endothelial β3-Adrenergic Receptor activation prevents pulmonary hypertension

This study shows that activating the endothelial β3-adrenergic receptor prevents pulmonary hypertension by improving vascular function and reducing remodeling.

Integrative Omics Identifies Candidate Plasma Biomarkers and Cellular Targets Associated with Thoracic Aortic Aneurysm

This study identifies 25 cellular subsets in thoracic aortic aneurysm tissue and links FGF-23 as a plasma biomarker associated with aortic diameter and disease.

Rare coding variants in 35 genes associate with circulating lipid levels: a multi-ancestry analysis of 170,000 exomes

This study identifies 35 genes associated with circulating lipid levels using rare coding variants from 170,000 exomes across multiple ancestries.

TP53-mediated clonal hematopoiesis confers increased risk for incident peripheral artery disease

This study shows that clonal hematopoiesis, especially with DDR gene mutations, increases the risk of peripheral artery disease and atherosclerosis.

Bringing the Pig to Comparative Neuroimaging: A Common Space Approach Contextualizes the Pig and Human Structural Connectome

This paper creates a common space for comparing pig and human structural connectomes to assess the translational validity of porcine neurological disease models.

Remote Ischemic Preconditioning Ameliorates Anthracycline-induced Cardiotoxicity and Preserves Mitochondrial Integrity

This study shows that remote ischemic preconditioning (RIPC) before doxorubicin injections reduces cardiotoxicity by preserving mitochondrial integrity and cardiac function in pigs.