Vladimir Roudko

This study identifies the role of mature dendritic cells type 1 in forming, maintaining, and functioning tertiary lymphoid structures in cancer.

The paper identifies TREM2-expressing macrophages as predictors of response to PD-1 blockade in HCC patients using clinical and spatial transcriptomic data.

This study identifies 25 cellular subsets in thoracic aortic aneurysm tissue and links FGF-23 as a plasma biomarker associated with aortic diameter and disease.

The paper maps T cell epitopes in SARS-CoV-2, showing that immunodominant regions are conserved across variants and important for immune surveillance.

MARQO pipeline automates single-cell analysis of multiplex immunostained tissue slides, showing improved accuracy over manual methods in cancer studies.

The paper benchmarks deconvolution tools for spatial transcriptomic data and introduces a novel pipeline to analyze tissue microenvironment dynamics.

This study identifies HNRNPM as a splicing factor critical for prostate cancer cell growth by regulating splicing fidelity and circRNA biogenesis, suggesting it as a therapeutic target.