María Villalba‐Orero

Endothelial β3-Adrenergic Receptor activation prevents pulmonary hypertension

This study shows that activating the endothelial β3-adrenergic receptor prevents pulmonary hypertension by improving vascular function and reducing remodeling.

Vascular HIF2 signaling prevents cardiomegaly, alveolar congestion and capillary remodeling during chronic hypoxia

This study shows that HIF2 signaling in the Wt1 lineage prevents cardiomegaly and pulmonary remodeling during chronic hypoxia but causes microvascular instability and cardiac dysfunction when absent.

PTBP1 promotes cardiac hypertrophy anddiastolic dysfunction by modulating alternativesplicing

The paper investigates alternative splicing (AS) in cardiac pathophysiology, identifying PTBP1 as a key regulator of AS changes that drive cardiac hypertrophy and diastolic dysfunction.