Author

Reini F. Luco

Centre National de la Recherche ScientifiqueORCID 0000-0002-9086-6507Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Yaiza Núñez‐Álvarez· 2 shared Alexandre FavereauxiD· 1 shared Alexandre SegelleiD· 1 shared Andrew OldfieldiD· 1 shared Ane Rubio-Zulaika· 1 shared Anne‐Aurélie RaymondiD· 1 shared Anthony BouteriD· 1 shared Cyril DourtheiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersMolecular Biology

Yaiza Núñez‐Álvarez

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Author profile →

3 papers

Recent·Most cited

Cancer cells transfer invasive properties through microRNAs contained in collagen-tracks

Léa Normand, Lucile Rouyer, Élodie Richard, Nathalie Allain, Julie Giraud, Sylvaine Di-Tommaso, Cyril Dourthe, Anne‐Aurélie Raymond, Jean‐William Dupuy, Kévin Moreau, Richard D Iggo, Gaetan McGrogan, Nathalie Dugot‐Senant, Anthony Bouter, Sisareuth Tan, , Frédéric Saltel

The paper identifies collagen-tracks as a new form of cell-cell communication that transfer invasive properties via miRNAs, promoting metastasis in breast cancer.

bioRxiv · Jan 25, 2025 · PreprintCell Biology

A CRISPR-dCas13 RNA-editing tool to study alternative splicing

Yaiza Núñez‐Álvarez, Tristan Espie-Caullet, Géraldine Buhagiar‐Labarchède, Ane Rubio-Zulaika, Josune Alonso‐Marañón, Elvira Luna-Pérez, Lorea Blázquez, Reini F. Luco

This paper introduces a CRISPR-dCas13 tool to manipulate alternative splicing patterns and identify regulatory RNA elements in a cost-effective manner.

Nucleic Acids Research · Jul 25, 2024Peer-reviewedMolecular Biology

Histone marks are drivers of the splicing changes necessary for an epithelial-to-mesenchymal transition

Alexandre Segelle, Yaiza Núñez‐Álvarez, Andrew Oldfield, Kimberly M. Webb, Philipp Voigt, Reini F. Luco

The paper shows that histone marks H3K27ac and H3K27me3 drive splicing changes during epithelial-to-mesenchymal transition by modulating splicing factor recruitment.

bioRxiv · May 4, 2021 · PreprintMolecular Biology