Author

Xinru Chen

Innovative Genomics InstituteORCID 0000-0002-9093-1911Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:CRISPR screen· 1 Approach:experimental assay· 1 Organism:mouse· 1 Research Focus:software / tool· 1 Approach:statistical model· 1 Organism:zebrafish· 1

Frequent Co-Authors

Alejandro Méndez‐MancillaiD· 1 shared Andreas O. FrankiD· 1 shared Barna D. FodoriD· 1 shared Christian E. StiegeriD· 1 shared Christina C. KuismiiD· 1 shared Cory M. JohannesseniD· 1 shared Daniel Fuller· 1 shared Daniel HaroiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperGenomics

Alejandro Méndez‐MancillaORCID

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2 papers

Recent·Most cited

BiochemistryACS Central SciencePeer-reviewedJun 11, 2026

Targeted Transcriptional Repression by Induced Proximity

Christian E. Stieger, Xinru Chen, Christina C. Kuismi…·Daniel K. Nomura

This paper introduces TRACERs, small-molecule drugs that silence transcription factors in cancer by recruiting repressor complexes, showing efficacy against ER and AR in breast and prostate cancer.

3 citations

humanexperimental assay

𝕏 PostBluesky

GenomicsCell GenomicsPeer-reviewedSep 3, 2021

Transcriptome-wide Cas13 guide RNA design for model organisms and viral RNA pathogens

Xinyi Guo, Jahan A. Rahman, Hans‐Hermann Wessels…·Neville E. Sanjana

The paper predicts Cas13 guide RNA efficacy for transcripts in model organisms and viral RNA pathogens and provides a web tool for gRNA design.

79 citations

humanmouse

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