Molecular BiologyNature Structural & Molecular BiologyPeer-reviewed
SARS-CoV-2 Nsp1 binds ribosomal mRNA channel to inhibit translation
Katharina Noel Schubert, Evangelos D. Karousis, Ahmad Jomaa…·Nenad Ban
This study shows SARS-CoV-2 Nsp1 binds to the 40S ribosomal subunit to inhibit translation by blocking mRNA entry, while viral mRNA enhances its own translation.
605 citationstop 1%