Author

Pritha Sen

Broad InstituteORCID 0000-0002-9102-4045Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:human· 3 Assay:scRNA-seq· 3 Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1

Frequent Co-Authors

Alexandra–Chloé VillaniiD· 2 shared Jayaraj RajagopaliD· 2 shared Rachelly NormandiD· 2 shared A ChatterjeeiD· 1 shared Adam L. Essene· 1 shared Adam L. HaberiD· 1 shared Adrien Antoinette· 1 shared Alex K. ShalekiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

Alexandra–Chloé VillaniORCID

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Author profile →

3 papers

Recent·Most cited

A Community-Driven Single-Cell PBMC Reference Integrating Landmark Datasets Spanning Health and Disease

Ana-Maria Cujba, Sergio Aguilar-Fernández, Adrien Antoinette, Wamia Said, Michaela Müller, Kian Hong Kock, Jacquelyn Nestor, Radhika Sonthalia, Eliora Violain Buyamin, Pragya Rawat, Alexander V. Predeus, Lorenz Kretschmer, Lijiang Fei, Kamil Slowikowski, Pritha Sen, , Gary Reynolds

HARP integrates PBMC data from multiple studies to create a reference atlas with consensus annotations and identifies age, sex, and disease-related cellular modules.

bioRxiv · Oct 21, 2026 · PreprintImmunology

Single-cell analysis of human airway epithelium identifies cell type-specific responses to Aspergillus and Coccidioides

Alfred T. Harding, Arianne J. Crossen, Jennifer L. Reedy, Kyle J. Basham, Olivia W. Hepworth, Yanting Zhang, Viral S. Shah, Hannah E. Brown, Manalee Vishnu Surve, Patricia Simaku, Geneva N. Kwaku, Kirstine Nolling Jensen, Yohana Otto, Rebecca Ward, George R. Thompson, , Jatin M. Vyas

This study uses single-cell RNA sequencing to analyze human airway epithelial cell responses to Aspergillus and Coccidioides, revealing distinct stress and cytokine pathways.

mBio · Oct 13, 2025Peer-reviewedImmunology

A single-cell and spatial atlas of autopsy tissues reveals pathology and cellular targets of SARS-CoV-2

Toni Marie Delorey, Carly G.K. Ziegler, Graham Heimberg, Rachelly Normand, Yiming Yang, Åsa Segerstolpe, Domenic Abbondanza, Stephen J. Fleming, Ayshwarya Subramanian, Daniel T. Montoro, Karthik A. Jagadeesh, Kushal K. Dey, Pritha Sen, Michal Slyper, Yered H. Pita-Juárez, , Alexandra–Chloé Villani

This study creates a single-cell and spatial atlas of autopsy tissues from COVID-19 patients, revealing altered cellular responses and potential therapeutic targets.

bioRxiv · Feb 25, 2021 · PreprintGenomics