Zachary Peters Wakefield

SpliceImpactR identifies and predicts the impact of alternative RNA processing events on protein function across the human transcriptome, revealing widespread context-dependent effects on the proteome.

Biosurfer identifies sources of protein isoform diversity by analyzing long-read RNA-seq data, revealing common mechanisms like alternative transcription start sites and 'ragged codons'.

This study shows that enhancing sleep restores memory in flies with damaged Mushroom Bodies, revealing a role for circadian rhythms in memory impairment.