Author

Juan Aldaco

Cedars-Sinai Medical CenterORCID 0000-0002-9109-2195Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Adolfo Garcı́a-OcañaiD· 1 shared Alberto PuglieseiD· 1 shared Andrew F. StewartiD· 1 shared Armando E. GiulianoiD· 1 shared Debbie C. ThurmondiD· 1 shared Eunjin OhiD· 1 shared Felipe Cortés‐LedesmaiD· 1 shared FOUAD R. KANDEELiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCell Biology

Adolfo Garcı́a-OcañaORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintSep 22, 2026

Harmine Plus Exendin-4 Enhances Remission of Recent-Onset Type 1 Diabetes Following Anti-CD3 Therapy

Geming Lu, RANDY KANG, MIGUEL VARELA…·Adolfo Garcı́a-Ocaña

This study shows that harmine plus exendin-4, when combined with anti-CD3 therapy, promotes beta-cell recovery and reduces immunogenicity, leading to remission of recent-onset type 1 diabetes.

DOI 10.64898/2026.09.21.753317

mouseexperimental assay

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Molecular BiologyNAR CancerPeer-reviewedMar 15, 2024

TDP 2 modulates the expression of estrogen-responsive oncogenes

Nicholas Manguso, Minhyung Kim, Neeraj Joshi…·Hisashi Tanaka

This study shows that TDP2 regulates estrogen-induced oncogene expression by resolving TOP2-induced DNA breaks, affecting MYC and CCND1 in ER-positive cells and mice.

4 citations

mousehuman

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