Author

Dora Hammerl

ORCID 0000-0002-9124-5665Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Alexandre PL MarraffaiD· 1 shared André KunertiD· 1 shared Christopher SchlieheiD· 1 shared Cor BerrevoetsiD· 1 shared Daphne RoelofsiD· 1 shared Kim KroeseiD· 1 shared Mandy van BrakeliD· 1 shared Margherita Mosiello· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Alexandre PL MarraffaORCID

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1 paper

Recent·Most cited

Adoptive cell therapy using T cell receptors equipped with ICOS yields durable anti-tumor response

Alexandre PL Marraffa, Cor Berrevoets, Margherita Mosiello, Rebecca Wijers, Daphne Roelofs, Mandy van Brakel, Kim Kroese, Marlies J. W. Peeters, Willem A. Dik, André Kunert, Rachel J.M. Abbott, Dora Hammerl, Christopher Schliehe, Reno Debets

This paper designs TCRs with ICOS to improve T cell therapy, showing durable anti-tumor effects and resistance to exhaustion in mice and humans.

bioRxiv · Oct 14, 2025 · PreprintImmunology