Author

Ryan Cho

The University of Texas Medical Branch at GalvestonORCID 0000-0002-9162-282XUnclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Ryan Cho1 paper · New York University

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Hema Prasad Narra· 2 shared Hui Wang· 2 shared Lihai Gao· 2 shared Lynn SoongiD· 2 shared Yixuan Zhou· 2 shared Yuejin LiangiD· 2 shared Casey Gonzales· 1 shared Dario Villacreses· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersImmunology

Hema Prasad Narra

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2 papers

Recent·Most cited

Inducible nitric oxide synthase (iNOS) regulates skin eschar lesions, bacterial persistence, and inflammatory resolution in mouse models of scrub typhus

Yixuan Zhou, Lihai Gao, Ryan Cho, Judy Ly, Hui Wang, Hema Prasad Narra, Kun‐Hsien Tsai, Lynn Soong, Yuejin Liang

This study investigates the role of iNOS in regulating skin lesions, bacterial persistence, and inflammation resolution during scrub typhus in mice, showing its dual function in antimicrobial defense and inflammation control.

bioRxiv · Apr 20, 2026 · PreprintImmunology

A Humanized IFN-γ Mouse Model Reveals Skin Eschar Formation, Enhanced Susceptibility and Scrub Typhus Pathogenesis

Ryan Cho, Lihai Gao, Hui Wang, Yixuan Zhou, Casey Gonzales, Dario Villacreses, Emmett A. Dews, Xiaofei Zhou, Ruili Lv, Hema Prasad Narra, Lynn Soong, Yuejin Liang

This study develops a humanized IFN-γ mouse model that shows increased susceptibility to Orientia tsutsugamushi infection, skin eschar formation, and immune dysregulation, mimicking human scrub typhus pathogenesis.

PLoS Pathogens · Feb 11, 2026Peer-reviewedImmunology