Author

Rafael Alis

Consejo Superior de Investigaciones CientíficasORCID 0000-0002-9169-5084Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Evolutionary Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Nuria FlamesiD· 2 shared Adrián Tarazona-SáncheziD· 1 shared Andrea Millán-TrejoiD· 1 shared Antonio Jordán· 1 shared Arantza BarriosiD· 1 shared Audrey KellyiD· 1 shared Benjamin Jones· 1 shared Carla Lloret-FernándeziD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersNeuroscience

Nuria FlamesORCID

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2 papers

Recent·Most cited

A postnatal molecular switch drives the activity-dependent maturation of parvalbumin interneurons

Monika Moissidis, Leyla Abbasova, Martijn M. Selten, Rafael Alis, Clémence Bernard, Yaiza Domínguez-Canterla, Fazal Oozeer, Shenyue Qin, Audrey Kelly, Laura Mòdol, Navneet A. Vasistha, Benjamin Jones, Pawan Dhami, Konstantin V. Khodosevich, Fursham Hamid, , Óscar Marín

This study identifies a molecular switch driven by neuronal activity and PGC-1 that promotes the maturation of parvalbumin interneurons during postnatal development.

Cell · Jul 16, 2025Peer-reviewedNeuroscience

Gene regulatory mechanisms underlying evolutionary adaptations of homologous neuronal cell types

Andrea Millán-Trejo, Carlos Mora‐Martínez, Adrián Tarazona-Sánchez, Carla Lloret-Fernández, Rafael Alis, Antonio Jordán, Arantza Barrios, Nuria Flames

This study identifies gene regulatory mechanisms that coordinate neuron-type-specific programs with plastic gene expression responses in Caenorhabditis species.

bioRxiv · Jan 30, 2025 · PreprintEvolutionary Biology