Author

Mariangela Sabatella

Erasmus MCORCID 0000-0002-9177-4946Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Hannes LansiD· 2 shared Karen L. ThijsseniD· 2 shared Melanie van der WoudeiD· 2 shared Wim VermeuleniD· 2 shared Carlota Davó-MartíneziD· 1 shared Dick H. W. DekkersiD· 1 shared Jeroen DemmersiD· 1 shared Jurgen A. F. MarteijniD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 25 mutual co-author links

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2 shared papersMolecular Biology

Hannes LansORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintMar 21, 2025

RNA polymerase II processing facilitates DNA repair and prevents DNA damage-induced neuronal and developmental failure

Melanie van der Woude, Karen L. Thijssen, Mariangela Sabatella…·Hannes Lans

This study shows that RNA polymerase II processing prevents DNA damage-induced neuronal and developmental failure in TC-NER defects by enabling backup repair pathways.

2 citations

C. elegansDNA methylation

𝕏 PostBluesky

GeneticsCommunications BiologyPeer-reviewedNov 25, 2021

C. elegans TFIIH subunit GTF-2H5/TTDA is a non-essential transcription factor indispensable for DNA repair

Karen L. Thijssen, Melanie van der Woude, Carlota Davó-Martínez…·Hannes Lans

This study shows that GTF-2H5 is essential for DNA repair in C. elegans but not for viability, highlighting its role in transcription and repair processes.

13 citations

C. elegansexperimental assay

𝕏 PostBluesky