Author

Thomas Svensson

Science for Life LaboratoryORCID 0000-0002-9190-2979Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1

Frequent Co-Authors

Jens NielseniD· 3 shared Diane HattoniD· 2 shared Johan RockbergiD· 2 shared Jonathan L. RobinsoniD· 2 shared Luigi GrassiiD· 2 shared Magdalena MalmiD· 2 shared Rasool SaghaleyniiD· 2 shared Véronique ChotteauiD· 2 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersSystems Biology

Jens NielsenORCID

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3 papers

Recent·Most cited

Standard-GEM supports reproducible development of genome-scale metabolic models

Mihail Anton, Eivind Almaas, Famke Bäuerle, Moritz E. Beber, Rui Benfeitas, Sara Benito-Vaquerizo, Lars M. Blank, Frederick Clasen, Claudia de Buck, Andreas Dräger, John M. Hancock, Vassily Hatzimanikatis A, Matthias König, Dimitra Lappa, Feiran Li, , Eduard Johannes Kerkhoven

Standard-GEM provides a template for reproducible genome-scale metabolic model development following FAIR principles and software best practices.

bioRxiv · Mar 21, 2023 · PreprintSystems Biology

Transcriptome analysis of EPO and GFP HEK293 Cell-lines Reveal Shifts in Energy and ER Capacity Support Improved Erythropoietin Production in HEK293F Cells

Rasool Saghaleyni, Magdalena Malm, Noah Moruzzi, Jan Zrimec, Ronia Razavi, Num Wistbacka, Hannes Thorell, Anton Pintar, Andreas Hober, Fredrik Edfors, Véronique Chotteau, Per‐Olof Berggren, Luigi Grassi, Aleksej Zelezniak, Thomas Svensson, , Johan Rockberg

The paper compares transcriptomic profiles of HEK293 cell lines producing erythropoietin or GFP to identify factors associated with improved erythropoietin production.

Cell Reports · Jun 1, 2022Peer-reviewedSystems Biology

Evolution from adherent to suspension - systems biology of HEK293 cell line development

Magdalena Malm, Rasool Saghaleyni, Magnus Lundqvist, Marco Giudici, Véronique Chotteau, Ray P. Field, Paul Varley, Diane Hatton, Luigi Grassi, Thomas Svensson, Mathias Uhlén, Jens Nielsen, Johan Rockberg

The paper analyzes genomic, transcriptomic, and metabolic changes in HEK293 cell lines to understand genetic and compositional differences between adherent and suspension derivatives.

Scientific Reports · Nov 4, 2020Peer-reviewedSystems Biology