Author

Andi Liu

The University of Texas Health Science Center at HoustonORCID 0000-0002-9193-6319Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Genetic & Genomic Medicine· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Assay:GWAS summary statistics· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Brisa Simões FernandesiD· 2 shared Zhongming ZhaoiD· 2 shared Astrid Marilyn ManueliD· 1 shared Chia-Hao TungiD· 1 shared Citu CituiD· 1 shared Claudio A. SotoiD· 1 shared Damian GorskiiD· 1 shared Jingchun CheniD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersNeuroscience

Brisa Simões FernandesORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Single-nucleus multiomics reveals the disrupted regulatory programs in three brain regions of sporadic early-onset Alzheimer's disease

Andi Liu, Citu Citu, Nitesh Enduru, Xian Chen, Chia-Hao Tung, Tirthankar Sinha, Sofia E. Sepulveda, Astrid Marilyn Manuel, Damian Gorski, Brisa Simões Fernandes, Meifang Yu, Paul Ernest Schulz, Lukas Mikolaj Simon, Claudio A. Soto, Zhongming Zhao

This study creates a single-nucleus multiome atlas of sEOAD brain regions, identifying key transcription factors and regulatory elements linked to disease.

Science Advances · Dec 17, 2025Peer-reviewedNeuroscience

GRPa-PRS: A risk stratification method to identify genetically-regulated pathways in polygenic diseases

Xiaoyang Li, Brisa Simões Fernandes, Andi Liu, Jingchun Chen, Xiangning Chen, Zhongming Zhao, Yulin Dai

GRPa-PRS identifies genetically-regulated pathways in polygenic diseases by stratifying individuals based on PRS and analyzing differential gene expression across risk strata.

Alzheimer s & Dementia · Oct 1, 2025Peer-reviewedGenetic & Genomic Medicine