NeuroscienceScientific ReportsPeer-reviewed
Human immune cells infiltrate the lesioned spinal cord and impair recovery after spinal cord injury in humanized mice
Randall S. Carpenter, Roselyn R. Jiang, Faith H. Brennan…·Phillip G. Popovich
This study shows that a mature human immune system in humanized mice, developed over 3-4 months, leads to worse spinal cord injury outcomes due to increased neuroinflammation.
18 citations