Phillip G. Popovich

This study identifies the oral cavity as a source of lung dysbiosis after spinal cord injury and shows that targeted antibiotic delivery reduces infection risk.

The paper predicts microbial ecosystem impact on host metabolism using genome-resolved metagenomics, identifying key species and pathways involved in nitrogen balance and host health.

This study shows that disrupting the spinal cord-gut axis alters gut microbial dynamics and carbohydrate cross-feeding, with interventions restoring health.

This paper shows spinal cord injury causes hematopoietic stem cells to enter a repressed state due to glucocorticoid surges, leading to long-term hematopoietic failure, which can be reversed by early glucocorticoid receptor blockade.

This study shows that EGFL7 promotes HSC expansion and survival, and its absence leads to reduced HSPC numbers and increased quiescence, with rEGFL7 treatment reversing these effects.

This study uses motion sequencing to analyze behavioral syllables after spinal cord injury, revealing recovery patterns shaped by injury severity and individual differences.

This paper shows that probiotic treatment after spinal cord injury improves gut health and respiratory function by reducing inflammation and enhancing neuronal regeneration.

This study shows that a mature human immune system in humanized mice, developed over 3-4 months, leads to worse spinal cord injury outcomes due to increased neuroinflammation.

This study shows that microglia reduce lesion size and improve recovery after spinal cord injury in mice by promoting astroglial encapsulation and limiting inflammation.