Author

Roselyn R. Jiang

McGill UniversityORCID 0000-0001-9596-5056Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Anastasia NijnikiD· 2 shared Bianca Pozzebon· 2 shared Danielle MaloiD· 2 shared David LanglaisiD· 2 shared Inés ColmegnaiD· 2 shared Joo Eun Kim· 2 shared Lin Tze Tung· 2 shared Mathieu ManciniiD· 2 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

Anastasia NijnikORCID

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3 papers

Recent·Most cited

Increased Expression and Altered Functional Activities of Immune Receptors TREM1, PD-L1, and Others on Hematopoietic Progenitor Cells in a Mouse Model of Rheumatoid Arthritis

Johanna M Toth, Roselyn R. Jiang, Lin Tze Tung, Dania Shaban, Mathieu Mancini, Bianca Pozzebon, Joo Eun Kim, Mitra Yousefi, Danielle Malo, Silvia Marina Vidal, Inés Colmegna, David Langlais, Anastasia Nijnik

This study shows that immune receptors on hematopoietic progenitor cells are upregulated in a mouse model of rheumatoid arthritis and that stimulating these receptors alters cell expansion and differentiation.

bioRxiv · Jun 12, 2026 · PreprintImmunology

Trained Immunity Affecting Dendritic Cell Differentiation and Function in Rheumatoid Arthritis

Lin Tze Tung, Roselyn R. Jiang, Bianca Pozzebon, Mathieu Mancini, Lucie Droin, Mitra Yousefi, Joo Eun Kim, Marwah Mousa, Yue Liang, Connie M. Krawczyk, Inés Colmegna, Danielle Malo, David Langlais, Silvia Marina Vidal, Anastasia Nijnik

This study shows that trained immunity affects dendritic cell differentiation and function in rheumatoid arthritis, altering their gene expression and immune responses.

bioRxiv · Feb 28, 2025 · PreprintImmunology

Human immune cells infiltrate the lesioned spinal cord and impair recovery after spinal cord injury in humanized mice

Randall S. Carpenter, Roselyn R. Jiang, Faith H. Brennan, Jodie C.E. Hall, Manoj K. Gottipati, Stefan Niewiesk, Phillip G. Popovich

This study shows that a mature human immune system in humanized mice, developed over 3-4 months, leads to worse spinal cord injury outcomes due to increased neuroinflammation.

Scientific Reports · Dec 13, 2019Peer-reviewedNeuroscience