NeuroscienceBrainPeer-reviewed
Reactive astrocytes promote proteostasis in Huntington disease through the JAK2-STAT3 pathway
Laurene Abjean, Lucile Ben Haim, Miriam Riquelme‐Perez…·Carole Escartin
This study shows that activating the JAK2-STAT3 pathway in astrocytes reduces mutant Huntingtin aggregates and improves disease outcomes in Huntington's disease models.
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