Anne‐Sophie Hérard

This study shows that activating the JAK2-STAT3 pathway in astrocytes reduces mutant Huntingtin aggregates and improves disease outcomes in Huntington's disease models.

This study shows that injecting human Alzheimer's brain extracts into mice with amyloid-beta plaques induces tau pathology, memory deficits, and synaptic loss, with neuritic plaques linked to synaptic impairment.

This study investigates the role of reactive astrocytes in Alzheimer's disease by modulating the JAK2-STAT3 pathway in 3xTg-AD mice, finding no effect on Tau or amyloid pathology but behavioral changes.