Transcription factors SP5 and SP8 drive primary cilia formation
Yinwen Liang, Richard P. Koche, Ravindra B. Chalamalasetty, Daniel N. Stephen, Mark W. L. Kennedy, Zhimin Lao, Yunong Pang, Ying-Yi Kuo, Moonsup Lee, Francisco Pereira Lobo, Xiaofeng Huang, Anna‐Katerina Hadjantonakis, Terry P. Yamaguchi, Kathryn V. Anderson, Alexandra L. Joyner
This study identifies SP5 and SP8 as transcription factors that drive primary cilia formation through genetic and transcriptomic analyses in mouse embryos.
Science · Aug 28, 2025Peer-reviewedDevelopmental Biology